Fig. 3
Coronal mice brain tissue sections stained with H&E: Cerebrum of Control group (A, A1), AB-PINACA group (B, B1), and MDMB-4en-PINACA group (C, C1), in addition, Hippocampus (stratum pyramidal), and Cerebellum of Control group (A2, A3), AB-PINACA group (B2, B3), and MDMB-4en-PINACA group (C2, C3), showed normal meninges (green arrow), normal capillaries (blue arrowheads), normal cerebral neurons (thin black arrows), normal neuroglia cells (black arrowheads), degenerated meninges (blue arrows), degenerated cerebral neurons (thick arrows), pyknotic glia cells (curved arrows), gliosis (circle), normal pyramidal neurons (zigzagged arrows), degenerated pyramidal neurons (straight lines), normal Purkinje cells(tailed arrows), degenerated Purkinje cells (red arrows), degenerated and congested capillaries (*), hemorrhage with inflammatory cells infiltration (square). All photomicrographs X400 except A, B, and C were X100