Skip to main content

Table 2 Recent study of oral dispersible tablets

From: Most promising solid dispersion technique of oral dispersible tablet

Sr. no Drug candidate Carrier used Solid dispersion technique used Ref. no
1 Lumacaft HPMC Spray drying [4]
2 Ritonavir PVP Melt extrusion [4]
3 Traconazole HPMC Melt extrusion [4]
4 Iopinavir and ritonavir PVP or polyvinyl acetate Melt extrusion [9]
5 Torcetrapib HPMC acetate succinate Spray drying [9]
6 Ibuprofen Various like starch 1500 PVP K 30 Melt extrusion [9, 36]
7 Verapamil Various Melt extrusion [9]
8 Troglitazone PVP Melt extrusion [9]
9 Tacrolimus HPMC Melt extrusion [9]
10 Etravirine HPMC Spray drying [9]
11 Everolimus HPMC Melt or spray drying [9]
12 Nifedipine PVP or polaxomer Melt or absorb on carrier [9]
13 Griseofulvin PEG Melt process [9]
14 Itraconazole HPMC, Gelucire 50/13, compritol 888ATOO Spray drying [9, 37]
15 Nabilone Providone [9]
16 Telaprevir HPMC Spray drying [38]
17 Nilvadipine HPMC Solvent evaporation method [38]
18 Vemurafinib HPMC Co-precipitation [38]
19 Ivacaftor HPMC Spray drying [38]
20 Tacrolimus HPMC Spray drying [38]
21 Everolimus HPMC Spray drying [38]
22 Silymarin PVP K 17 Supercritical fluid technology [39]
23 Polypeptide-K Trehalose Tween 80 Spray drying [40]
24 Valsartan PEG 6000 HPMC-100 kV Freeze drying [41]
25 Curcumin Eudragit EPO Solvent evaporation method [42]
26 Tadalafin PVP, malic acid or meglumine and aerosil 200 Solvent evaporation method [43]
27 Pseudomonas podoviridine phase PEV2 Trehalose, mannitol, l-leucine Spray drying [44]
28 Paracetamol Ethyl cellulose, mesoporous silica Fluid bed system [45]
29 Itraconazole Sucrose Centrifugal spinning method [46]
30 Olanzapine Sucrose, pregelatinized starch, sodium starch, glycolate Centrifugal spinning method [46, 47]
31 Piroxicam Sucrose Centrifugal spinning method [46]
32 Atrovastatin Mannitol, PEG 4000, PVP K 30 Hot melt and solvent evaporation method [48]
33 Alprazolam PEG 6000, PVP K 30 Solvent evaporation [49]
34 Aceciofenac Starch phosphate, Gelucire 50/13 Kneading method [50]
35 Carvedilol PEG 6000, Polaxomer407, HPMC, SSG Fusion and solvent evaporation [51]
36 Cefdinir PVP K 30, PEG 4000 Melt fusion and solvent evaporation [52]
37 Diacerein PVP K 30, HPMC Solvent evaporation [53]
38 Etoricoxib Lactose, sucrose, mannitol Solvent evaporation [54]
39 Glipizide HPMC, croscarmellose Solvent evaporation [55]
40 Mefenamic acid PEG 6000, PVP K 30, HPMC, MCC Kneading method [56]
41 Nalidixic acid PVP, beta cyclodextrin, SSG Solvent evaporation method [57]
42 Rofecoxib PEG 6000, PVP K 30 Fusion and solvent evaporation method [58]
43 Simvastatin PEG 4000, PVP K 30 Solvent evaporation method [59]
44 Stranidazole PEG 4000, PVP K 30 Solvent evaporation method [60]
45 Meloxicam PVP PEG 6000 Solvent evaporation method [61]
46 Telmisartan Gelucire 43/01, polaxomer407, PVP-K 30, HPMC E4, PEG 6000 Fusion method [62]
47 Gliclazide PEG 4000, PEG 6000, PVP K 30 Fusion and solvent evaporation method [63]
48 Proglitazone PEG 4000, PEG 6000, PEG 20000 Hot melt method
Microwave and kneading method
[64]
49 Carbamazepine Croscarmellose, SSG Solvent evaporation method [65]
50 Mesalamine SLS, urea, methanol Kneading method [66]
51 Ketoprofen PVP K 30, urea, mannitol, Tween 80 Solvent evaporation method [67]
52 Indomethacin Lactose monohydrate, PEG 6000, HPMC, povdone Kneading method [68]
53 Clonazepam PEG 6000, HPMC, polaxomer 407 Solvent evaporation method [69]
54 Telmisartan Beta cyclodextrin, MCC PH 102, polaxomer 188,400 Solvent evaporation method [70, 71]
55 Carvediol Beta cyclodextrin, MCC PH 102, polaxomer 188 Solvent evaporation method [72]
55 Chlorpheniramine maleate PEG 6000 and SSG Fusion method [73]
56 Nevirapine Urea and PEG Kneading method [74]