Agliardi G, Liuzzi AR, Hotblack A, De Feo D, Núñez N, Stowe CL, Friebel E, Nannini F, Rindlisbacher L, Roberts TA, Ramasawmy R, Williams IP, Siow BM, Lythgoe MF, Kalber TL, Quezada SA, Pule MA, Tugues S, Straathof K, Becher B (2021) Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma. Nat Commun 12:1–11. https://doi.org/10.1038/s41467-020-20599-x
Article
CAS
Google Scholar
Ahmed N, Brawley VS, Hegde M, Robertson C, Ghazi A, Gerken C, Liu E, Dakhova O, Ashoori A, Corder A, Gray T, Wu M, Liu H, Hicks J, Rainusso N, Dotti G, Mei Z, Grilley B, Gee A, Rooney CM, Brenner MK, Heslop HE, Wels WS, Wang LL, Anderson P, Gottschalk S (2015) Human epidermal growth factor receptor 2 (HER2)—Specific chimeric antigen receptor—modified T cells for the immunotherapy of HER2-Positive Sarcoma. J Clin Oncol 33:1688–1696. https://doi.org/10.1200/JCO.2014.58.0225
Article
CAS
PubMed
PubMed Central
Google Scholar
Akce M, Zaidi MY, Waller EK, El-rayes BF (2018) The potential of CAR T cell therapy in pancreatic. Cancer 9:1–11. https://doi.org/10.3389/fimmu.2018.02166
Article
CAS
Google Scholar
Akkın S, Varan G, Bilensoy E (2021) A review on cancer immunotherapy and applications of nanotechnology to chemoimmunotherapy of different cancers. Molecules. https://doi.org/10.3390/molecules26113382
Article
PubMed
PubMed Central
Google Scholar
Aparicio C, Belver M, Espeso F, Ana S, Miguel Á, Fuente D, Gonz M (2021) Cell therapy for colorectal cancer: the promise of chimeric antigen receptor (CAR) -T Cells. Int J Mol Sci 22:11781
Article
CAS
Google Scholar
Appleton E, Hassan J, Chan C, Hak W, Sivamanoharan N, Wilkins A, Samson A, Ono M, Harrington KJ, Melcher A, Wennerberg E (2021) Kickstarting immunity in cold tumours: localised tumour therapy combinations with immune checkpoint blockade. Front Immunol 12:1–21. https://doi.org/10.3389/fimmu.2021.754436
Article
CAS
Google Scholar
Ajina A, Maher J (2019) Europe PMC Funders Group strategies to address chimeric antigen receptor tonic signalling. https://doi.org/10.1158/1535-7163.MCT-17-1097
Andrea AE, Chiron A, Bessoles S, Hacein-Bey-abina S (2020) Engineering next-generation car-t cells for better toxicity management. Int J Mol Sci 21:1–25. https://doi.org/10.3390/ijms21228620
Article
CAS
Google Scholar
Bedoya DM, Dutoit V, Migliorini D (2021) Allogeneic CAR T cells: an alternative to overcome challenges of CAR T cell therapy in glioblastoma. Front Immunol. https://doi.org/10.3389/fimmu.2021.640082
Article
PubMed
PubMed Central
Google Scholar
Bracaglia (2017) 乳鼠心肌提取 HHS public access. Physiol Behav 176:139–148. https://doi.org/10.1016/j.jcyt.2019.12.004
Bruno A, Salemme V, Centonze G, Cavallo F, De P (2021) The crosstalk between tumor cells and the immune microenvironment in breast cancer: implications for Immunotherapy. Front Oncol 11:1–20. https://doi.org/10.3389/fonc.2021.610303
Article
Google Scholar
Bair SM, Porter DL (2019) Accelerating chimeric antigen receptor therapy in chronic lymphocytic leukemia: the development and challenges of chimeric antigen receptor T-cell therapy for chronic lymphocytic leukemia. Am J Hematol 94:10–17. https://doi.org/10.1002/ajh.25457
Article
CAS
Google Scholar
Barrueto L, Caminero F, Cash L, Makris C, Lamichhane P, Deshmukh RR (2020) Resistance to checkpoint inhibition in cancer immunotherapy. Transl Oncol 13:100738. https://doi.org/10.1016/j.tranon.2019.12.010
Article
PubMed
PubMed Central
Google Scholar
Bedard PL, Hansen AR, Ratain MJ, Siu LL, Centre MC (2017) HHS Public Access 501:355–364. https://doi.org/10.1038/nature12627.Tumour
Bell M, Gottschalk S (2021) Engineered cytokine signaling to improve CAR T cell effector function. Front Immunol 12:1–16. https://doi.org/10.3389/fimmu.2021.684642
Article
CAS
Google Scholar
Beyes S, Bediaga NG, Zippo A (2021) An epigenetic perspective on intra-tumour heterogeneity : novel insights and new challenges from multiple fields. Cancers 13:4969
Article
CAS
Google Scholar
Boissel L, Betancur M, Lu W, Krause D, Van R, Wels W, Klingemann H, Boissel L, Betancur M, Lu W, Krause D, Van R, Boissel L, Betancur-boissel M, Lu W, Krause DS (2013) Retargeting NK-92 cells utilizing CD19- compares favorably with antibody-dependent cellular cytotoxicity retargeting NK-92 cells using CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody- dependent cellular cytotoxi. OncoImmunology 2:e26527. https://doi.org/10.4161/onci.26527
Article
PubMed
PubMed Central
Google Scholar
Chen X, Amar N, Zhu Y, Wang C, Xia C, Yang X, Wu D, Feng M (2020) Combined DLL3- targeted bispecific antibody with PD-1 inhibition is efficient to suppress small cell lung cancer growth. J Immunother Cancer 8:e000785. https://doi.org/10.1136/jitc-2020-000785
Article
PubMed
PubMed Central
Google Scholar
Caliendo F, Dukhinova M, Siciliano V (2019) Engineered cell-based therapeutics: synthetic biology meets immunology. Front Bioeng Biotechnol 7:1–8. https://doi.org/10.3389/fbioe.2019.00043
Article
Google Scholar
Caruso HG, Heimberger AB, Cooper LJN (2019) Steering CAR T cells to distinguish friend from foe. OncoImmunology. https://doi.org/10.1080/2162402X.2016.1271857
Article
PubMed
PubMed Central
Google Scholar
Caswell DR, Swanton C (2017) The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome. BMC Med 15:1–9. https://doi.org/10.1186/s12916-017-0900-y
Article
CAS
Google Scholar
Cells CART, Benmebarek M, Karches CH, Cadilha BL, Lesch S, Endres S, Kobold S (2019) Killing mechanisms of chimeric antigen receptor. Int J Mol Sci. https://doi.org/10.3390/ijms20061283
Article
Google Scholar
Chmielewski M (2020) TRUCKS, the fourth-generation CAR T cells: current developments and clinical translation. Adv Cell Gene Ther 3:1–9. https://doi.org/10.1002/acg2.84
Article
CAS
Google Scholar
Cooperation W, Guo F, Cui J (2021) CAR-T in cancer treatment : develop in self-optimization
Dexter A Jr, August B (2018) CAR T cells in solid tumors: blueprints for building effective therapies 9:1–20. https://doi.org/10.3389/fimmu.2018.01740
Dong Y, Wan Z, Gao X, Yang G, Liu L (2021) Reprogramming immune cells for enhanced cancer immunotherapy: targets and strategies. Front Immunol 12:1–14. https://doi.org/10.3389/fimmu.2021.609762
Article
CAS
Google Scholar
Dummer RG (2018) Anti-PD-1 and anti-CTLA-4 therapies in cancer : mechanisms of action, efficacy, and limitations. Front Oncol 8:1–14. https://doi.org/10.3389/fonc.2018.00086
Article
CAS
Google Scholar
Dhatchinamoorthy K, Colbert JD, Rock KL (2021) Cancer immune evasion through loss of MHC class I antigen presentation. Front Immunol. https://doi.org/10.3389/fimmu.2021.636568
Article
PubMed
PubMed Central
Google Scholar
Duel C, Spear C, Shield T, Jo Y, Ali LA, Shim JA, Lee BH, Hong C (2020) Innovative CAR-T cell therapy for solid tumor
Dana H, Mahmoodi G, Amir S, Reza H, Grupp SA, Webster TJ, Rabello E, Rapo C (2021) CAR-T cells: early successes in blood cancer and challenges in solid tumors. Acta Pharmaceutica Sinica B 11:1129–1147. https://doi.org/10.1016/j.apsb.2020.10.020
Article
CAS
PubMed
Google Scholar
Dees S, Ganesan R, Singh S, Grewal IS (2020) Emerging CAR-T cell therapy for the treatment of triple-negative breast cancer. Mol Cancer Ther 19:2409–2421. https://doi.org/10.1158/1535-7163.MCT-20-0385
Article
CAS
PubMed
Google Scholar
Ehx G, Perreault C (2019) Discovery and characterization of actionable tumor antigens. Genome Med 11:10–12
Article
Google Scholar
Evgin L, Vile RG (2021) Parking CAR T cells in tumours: oncolytic viruses as valets or vandals ? Cancers 13:1106
Article
CAS
Google Scholar
Georgiadis C, Preece R, Nickolay L, Etuk A, Petrova A, Ladon D, Danyi A, Humphryes-kirilov N, Ajetunmobi A, Kim D, Kim J, Qasim W (2018) Long Terminal repeat CRISPR-CAR-coupled “Universal” T cells mediate potent anti-leukemic effects. Mol Ther 26:1215–1227. https://doi.org/10.1016/j.ymthe.2018.02.025
Article
CAS
PubMed
PubMed Central
Google Scholar
Gill N, Paltser G, Ashkar AA (2009) Interleukin-15 expression affects homeostasis and function of B cells through NK cell-derived interferon- c. Cell Immunol 15:1–6. https://doi.org/10.1016/j.cellimm.2009.03.010
Article
CAS
Google Scholar
Gowrishankar K, Birtwistle L, Micklethwaite K (2018) Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells. Mamm Genome. https://doi.org/10.1007/s00335-018-9756-5
Article
PubMed
Google Scholar
Guedan S, Calderon H, Posey AD, Maus MV (2019) Engineering and design of chimeric antigen receptors. Mol Ther Methods Clin Dev 12:145–156. https://doi.org/10.1016/j.omtm.2018.12.009
Article
CAS
PubMed
Google Scholar
Guo C, Wu M, Lu Y (2020) Effective antitumor activity of 5T4-specific CAR-T cells against ovarian cancer cells in vitro and xenotransplanted tumors in vivo. MedComm 1:338–350. https://doi.org/10.1002/mco2.34
Article
PubMed
PubMed Central
Google Scholar
Han D, Xu Z, Zhuang Y, Ye Z, Qian Q (2021) Current progress in CAR-T cell therapy for hematological malignancies. J Cancer 12:326–334. https://doi.org/10.7150/JCA.48976
Article
CAS
PubMed
PubMed Central
Google Scholar
Han X, Wang Y, Wei J, Han W (2019) Multi-antigen-targeted chimeric antigen receptor T cells for cancer therapy. J Hematol Oncol 12:1–10. https://doi.org/10.1186/s13045-019-0813-7
Article
Google Scholar
Hartnett EG, Knight J, Radolec M, Buckanovich RJ, Edwards RP, Vlad AM (2020) Immunotherapy advances for epithelial ovarian cancer. Cancers 12:1–27. https://doi.org/10.3390/cancers12123733
Article
CAS
Google Scholar
Hemminki O, Manuel J, Hemminki A (2020) Oncolytic viruses for cancer immunotherapy. J Hematol Oncol 1:1–15
Google Scholar
Hoteit M, Oneissi Z, Reda R, Wakim F, Zaidan A, Farran M, Abi-Khalil E, El-Sibai M (2021) Cancer immunotherapy: a comprehensive appraisal of its modes of application (review). Oncol Lett. https://doi.org/10.3892/ol.2021.12916
Article
PubMed
PubMed Central
Google Scholar
Huemer F, Leisch M, Geisberger R, Melchardt T, Rinnerthaler G, Zaborsky N, Greil R (2017) Combination strategies for immune-checkpoint blockade and response prediction by Artificial Intelligence. Int J Mol Sci 4:1–35
Google Scholar
Hassanpour SH, Dehghani M (2017) Review of cancer from perspective of molecular. J Cancer Res Pract 4:127–129. https://doi.org/10.1016/j.jcrpr.2017.07.001
Article
Google Scholar
Hematol J, Edeline J, Houot R, Marabelle A, Alcantara M (2021) CAR-T cells and BiTEs in solid tumors: challenges and perspectives. J Hematol Oncol. https://doi.org/10.1186/s13045-021-01067-5
Article
Google Scholar
Hematol J, Tian Z, Liu M, Zhang Y, Wang X (2021) Bispecific T cell engagers: an emerging therapy for management of hematologic malignancies. J Hematol Oncol. https://doi.org/10.1186/s13045-021-01084-4
Article
Google Scholar
Hou AJ, Chang ZL, Lorenzini MH, Zah E, Chen YY (2018) TGF- b – responsive CAR-T cells promote anti-tumor immune function. Bioeng Transl Med 3:75–86. https://doi.org/10.1002/btm2.10097
Article
CAS
PubMed
PubMed Central
Google Scholar
Hughes-parry HE, Cross RS, Jenkins MR (2019) The evolving protein engineering in the design of chimeric antigen receptor T cells. Int J Mol Sci 21:204
Article
Google Scholar
Isidoro-García M, Dávila I, Laffond E, Moreno E, Lorente F, González-Sarmiento R (2005) Polymorphisms in asthma: a case control study. Clin Mol Allergy 4:1–7. https://doi.org/10.1186/1476-7961-3-15
Article
CAS
Google Scholar
Jaspers JE, Brentjens RJ, Sloan M, Cancer K, Sloan M, Cancer K, Program C, Sloan M, Cancer K (2017) HHS Public Access 28:83–91. https://doi.org/10.1016/j.pharmthera.2017.03.012
Ji F, Zhang F, Zhang M, Long K, Xia M, Lu F, Li E, Chen J, Li J, Chen Z, Jing L, Jia S, Yang R, Hu Z, Guo Z (2021) Targeting the DNA damage response enhances CD70 CAR-T cell therapy for renal carcinoma by activating the cGAS-STING pathway. J Hematol Oncol 14:1–5. https://doi.org/10.1186/s13045-021-01168-1
Article
CAS
Google Scholar
Jin KT, Chen B, Liu YY, Lan HR, Yan JP (2021) Monoclonal antibodies and chimeric antigen receptor (CAR) T cells in the treatment of colorectal cancer. Cancer Cell Int. https://doi.org/10.1186/s12935-021-01763-9
Article
PubMed
PubMed Central
Google Scholar
Jin L, Cao L, Zhu Y, Cao J, Li X, Zhou J, Liu B (2021) Enhance anti-lung tumor efficacy of chimeric antigen receptor-T cells by ectopic expression of C–C motif chemokine receptor 6. Sci Bull 66:803–812. https://doi.org/10.1016/j.scib.2020.12.027
Article
CAS
Google Scholar
Junttila IS (2018) Tuning the Cytokine Responses : An Update on interleukin (iL)-4 and iL-13 receptor complexes. Front Immunol. https://doi.org/10.3389/fimmu.2018.00888
Article
PubMed
PubMed Central
Google Scholar
Koristka S, Ziller-Walter P, Bergmann R, Arndt C, Feldmann A, Kegler A, Cartellieri M, Ehninger A, Ehninger G, Bornhäuser M, Bachmann MP (2019) Anti-CAR-engineered T cells for epitope-based elimination of autologous CAR T cells. Cancer Immunol Immunother 68:1401–1415. https://doi.org/10.1007/s00262-019-02376-y
Article
CAS
PubMed
PubMed Central
Google Scholar
Kowalski J, Rzyman W, Biernat W, Montesano C, Bernardini R, Marek-Trzonkowska N (2020) Adoptive cell therapy—harnessing antigen-specific T cells to target solid tumours 1–30
Kim K, Gwak H, Han N, Hong EK, Choi BK, Cho H, Lee S, Lee Y, Nam KT, Song S (2021) Chimeric antigen receptor T cells with modified interleukin-13 preferentially recognize IL13R a 2 and suppress malignant glioma: a preclinical study. Front Immunol 12:1–13. https://doi.org/10.3389/fimmu.2021.715000
Article
Google Scholar
Kozani PS, Kozani PS, Rahbarizadeh F, Olive D (2021) Strategies for dodging the obstacles in CAR T cell therapy. Front Oncol 11:1–20. https://doi.org/10.3389/fonc.2021.627549
Article
Google Scholar
Lanitis E, Kosti P, Ronet C, Cribioli E, Rota G, Spill A, Reichenbach P, Zoete V, Laniti DD, Coukos G, Irving M, Car V (2021) VEGFR-2 redirected CAR-T cells are functionally impaired by soluble A competition for receptor binding. J Immunother Cancer 8:1–13. https://doi.org/10.1136/jitc-2020-002151
Article
Google Scholar
Li C, Jiang P, Wei S, Xu X, Wang J (2020) Regulatory T cells in tumor microenvironment : new mechanisms , potential therapeutic strategies and future prospects. Mol Cancer 1–23
Li H, Yang Y, Hong W, Huang M, Wu M, Zhao X (2020) Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects. Signal Transduct Target Ther. https://doi.org/10.1038/s41392-019-0089-y
Article
PubMed
PubMed Central
Google Scholar
Ligtenberg MA, Mougiakakos D, Mukhopadhyay M, Witt K, Lladser A, Chmielewski M, Riet T, Abken H, Kiessling R (2016) Coexpressed catalase protects chimeric antigen receptor-redirected T cells as well as bystander cells from oxidative stress-induced loss of antitumor activity. J Immunol 196:759–766. https://doi.org/10.4049/jimmunol.1401710
Article
CAS
PubMed
Google Scholar
Liu B, Yan L, Zhou M (2019) Target selection of CAR T cell therapy in accordance with the TME for solid tumors. Am J Cancer Res 9:228–241
CAS
PubMed
PubMed Central
Google Scholar
Long KB, Young RM, Boesteanu AC, Davis MM, Melenhorst JJ, Lacey SF, Degaramo DA, Levine BL, Fraietta JA (2018) CAR T cell therapy of non-hematopoietic malignancies: detours on the road to clinical success. Front Immunol 9:15. https://doi.org/10.3389/fimmu.2018.02740
Article
CAS
Google Scholar
Lu R, Hwang Y, Liu I, Lee C, Tsai H, Li H, Wu H (2020) Development of therapeutic antibodies for the treatment of diseases 1–30
Lee Ventola C (2017) Cancer immunotherapy, part 1: current strategies and agents. Pharm Ther 42:375–383
Google Scholar
Li T, Zhang F, Cao Y, Ning S, Bi Y, Xue W, Ren L (2017) Primary Ewing’s sarcoma/primitive neuroectodermal tumor of the ileum: case report of a 16-year-old Chinese female and literature review. Diagn Pathol 12:1–9. https://doi.org/10.1186/s13000-017-0626-3
Article
Google Scholar
Lin WY, Wang HH, Chen YW, Lin CF, Fan HC, Lee YY (2020) Gene modified car-t cellular therapy for hematologic malignancies. Int J Mol Sci 21:1–21. https://doi.org/10.3390/ijms21228655
Article
CAS
Google Scholar
Long L, Zhang X, Chen F, Pan Q, Phiphatwatchara P (2018) The promising immune checkpoint LAG-3: microenvironment to cancer immunotherapy from tumor. Genes Cancer 9:176–189
Article
CAS
Google Scholar
Maggs L, Cattaneo G, Dal AE, Moghaddam AS, Ferrone S (2021) CAR T cell-based immunotherapy for the treatment of glioblastoma. Front Neurosci 15:17. https://doi.org/10.3389/fnins.2021.662064
Article
Google Scholar
Marofi F, Motavalli R, Safonov VA, Thangavelu L, Yumashev AV, Alexander M, Shomali N, Chartrand MS, Pathak Y, Jarahian M (2021) CAR T cells in solid tumors : challenges and opportunities. Stem Cell Res Ther 1:1–16
Google Scholar
Marofi F, Rahman HS, Al-Obaidi ZMJ, Jalil AT, Abdelbasset WK, Suksatan W, Dorofeev AE, Shomali N, Chartrand MS, Pathak Y, Hassanzadeh A, Baradaran B, Ahmadi M, Saeedi H, Tahmasebi S, Jarahian M (2021) Novel CAR T therapy is a ray of hope in the treatment of seriously ill AML patients. Stem Cell Res Ther 12:1–23. https://doi.org/10.1186/s13287-021-02420-8
Article
CAS
Google Scholar
Muralidhar D, Vasugi GA, Sundaram S (2021) Incidence and demographic profile of Ewings sarcoma: experience from a tertiary care Hospital. Cureus 2021:1–12. https://doi.org/10.7759/cureus.18339
Article
Google Scholar
Morotti M, Albukhari A, Alsaadi A, Artibani M, Brenton JD, Curbishley SM, Dong T, Dustin ML, Hu Z, Mcgranahan N, Miller ML, Santana-gonzalez L, Seymour LW, Shi T, Loo PV, Yau C, White H, Wietek N, Church DN (2021) Promises and challenges of adoptive T-cell therapies for solid tumours. Br J Cancer. https://doi.org/10.1038/s41416-021-01353-6
Article
PubMed
PubMed Central
Google Scholar
Martinez M, Moon EK (2019) CAR T cells for solid tumors: new Strategies for finding infiltrating, and surviving in the tumor microenvironment. Front Immunol 10:1–21. https://doi.org/10.3389/fimmu.2019.00128
Article
CAS
Google Scholar
Mavilio, F., 2021. Designing lentiviral vectors for gene therapy of genetic diseases 1–14
Mo F, Duan S, Jiang X, Yang X, Hou X, Shi W, Carlos CJJ, Liu A, Yin S, Wang W, Yao H, Yu Z, Tang Z, Xie S, Ding Z, Zhao X, Hammock BD, Lu X (2021) Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor immunotherapy. Signal Transduct Target Ther. https://doi.org/10.1038/s41392-021-00462-1
Article
PubMed
PubMed Central
Google Scholar
Morgan MA, Schambach A (2018) Engineering CAR-T cells for improved function against solid tumors. Front Immunol 9:2493. https://doi.org/10.3389/fimmu.2018.02493
Article
CAS
PubMed
PubMed Central
Google Scholar
Nimmagadda S, Penet MF (2020) Ovarian cancer targeted theranostics. Front Oncol 9:1–13. https://doi.org/10.3389/fonc.2019.01537
Article
Google Scholar
Od Z, Condori J, Peterson N, Zhou S, Krenciute G (2020) Integration and expression in T cells: protocol and application for T-cell therapy
Pinel S, Thomas N, Boura C, Barberi-heyob M, Pinel S, Thomas N, Boura C, Approaches MB, Pinel S, Thomas N, Boura C, Barberi-heyob M (2019) Approaches to physical stimulation of metallic nanoparticles for glioblastoma treatment To cite this version : HAL Id : hal-01935483 Approaches to physical stimulation of metallic nanoparticles for glioblastoma treatment. Adv Drug Deliv Rev. https://doi.org/10.1016/j.addr.2018.10.013
Article
PubMed
Google Scholar
Poorebrahim M, Melief J, Coaña YPD, Wickström SL, Cid-arregui A, Kiessling R (2021) Counteracting CAR T cell dysfunction. Oncogene. https://doi.org/10.1038/s41388-020-01501-x
Article
PubMed
PubMed Central
Google Scholar
Pan Y, Yu Y, Wang X, Zhang T (2020) Tumor-associated macrophages in tumor immunity. Front Immunol. https://doi.org/10.3389/fimmu.2020.583084
Article
PubMed
PubMed Central
Google Scholar
Patterson JD, Henson JC, Breese RO, Bielamowicz KJ (2020) CAR T cell therapy for pediatric brain tumors. Front Oncol 10:1–14. https://doi.org/10.3389/fonc.2020.01582
Article
Google Scholar
Pharmd UP, Ms JA, Savani BN (2022) Review CAR T cell therapy in solid tumors : a review of current clinical trials. EJHaem 3:24–31. https://doi.org/10.1002/jha2.356
Article
Google Scholar
Pucci C, Martinelli C, Ciofani G (2019) Innovative approaches for cancer treatment: current perspectives and new challenges. Ecancermedicalscience 13:1–26. https://doi.org/10.3332/ecancer.2019.961
Article
Google Scholar
Qin S, Xu L, Yi M, Yu S, Wu K (2019) Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4 1–14
Quintarelli C, Orlando D, Boffa I, Guercio M, Assunta V (2018) Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma. OncoImmunology 7:1–16. https://doi.org/10.1080/2162402X.2018.1433518
Article
Google Scholar
Rafiq S, Hackett CS, Brentjens RJ (2020) Therapy. Nat Rev Clin Oncol. https://doi.org/10.1038/s41571-019-0297-y
Article
PubMed
Google Scholar
Ramachandran S, Verma AK, Dev K, Goyal Y, Bhatt D, Alsahli MA, Rahmani AH, Almatroudi A, Almatroodi SA, Alrumaihi F, Khan NA (2021) Review article role of cytokines and chemokines in NSCLC immune navigation and proliferation. Oxid Med Cell Longev 2021:1–20
Article
Google Scholar
Razeghian E, Nasution MKM, Rahman HS, Gardanova ZR (2021) A deep insight into CRISPR/Cas9 application in CAR-T cell-based tumor immunotherapies. Stem Cell Res Ther 7:1–17
Google Scholar
Redeker A, Arens R (2016) Improving adoptive T cell therapy: The particular role of T cell costimulation, cytokines, and post-transfer vaccination. Front Immunol 7:1–17. https://doi.org/10.3389/fimmu.2016.00345
Article
CAS
Google Scholar
Richards DM, Sefrin JP, Gieffers C, Hill O, Merz C (2020) Concepts for agonistic targeting of CD40 in immuno-oncology. Hum Vaccin Immunother 16:377–387. https://doi.org/10.1080/21645515.2019.1653744
Article
CAS
PubMed
Google Scholar
Roberto RBD, Castellanos-rueda R, Frey S, Egli D, Vazquez-lombardi R, Kapetanovic E, Kucharczyk J, Reddy ST (2020) A functional screening strategy for engineering chimeric antigen receptors with reduced on-target, off-tumor activation. Mol Ther 28:2564–2576. https://doi.org/10.1016/j.ymthe.2020.08.003
Article
CAS
PubMed
PubMed Central
Google Scholar
Rodriguez-garcia A, Palazon A, Noguera-ortega E Jr, D.J.P., Martin, F., (2020) CAR-T cells hit the tumor microenvironment : strategies to overcome tumor escape. Front Immunol 11:1–17. https://doi.org/10.3389/fimmu.2020.01109
Article
CAS
Google Scholar
Rosenblatt E, Zubizarreta E (n.d.) Radiotherapy in cancer care : facing the
Srivastava S, Riddell SR, Hutchinson F (2019) HHS Public Access 200:459–468. https://doi.org/10.4049/jimmunol.1701155.CAR
Kozani S, Pouya SK, Pooria R, F., (2021) CAR-T cell therapy in T-cell malignancies: Is success a low-hanging fruit? Stem Cell Res Ther 12:1–17. https://doi.org/10.1186/s13287-021-02595-0
Article
CAS
Google Scholar
Stoiber S, Cadilha BL, Benmebarek M-R, Lesch S, Endres S, Kobold S (2019) Limitations in the design of chimeric antigen receptors for cancer therapy. Cells 8:472. https://doi.org/10.3390/cells8050472
Article
CAS
PubMed Central
Google Scholar
Strohl N (2019) Bispecific T-cell redirection versus chimeric antigen receptor (CAR)-T cells as approaches to kill cancer cells. Antibodies 8:41. https://doi.org/10.3390/antib8030041
Article
CAS
PubMed Central
Google Scholar
Schmitt M, Greten FR (2021) The inflammatory pathogenesis of colorectal cancer. Nat Rev Immunol 21:653–667. https://doi.org/10.1038/s41577-021-00534-x
Article
CAS
PubMed
Google Scholar
Souza RRD (2021) Biologics: targets and therapy armored CAR T-cells : the next chapter in T-cell cancer immunotherapy. Biolog Targets Ther 15:95–105
Article
Google Scholar
Schiavone G, Epistolio S, Martin V, Molinari F, Barizzi J, Mazzucchelli L, Frattini M, Wannesson L (2020) Correction to: Functional and clinical significance of ROR1 in lung adenocarcinoma (BMC Cancer, (2020), 20, 1, (1085), DOI: 10.1186/s12885-020-07587-6). BMC Cancer 20:1–7. https://doi.org/10.1186/s12885-020-07704-5
Article
Google Scholar
Sur D, Havasi A, Cainap C, Samasca G, Burz C (2020) Chimeric antigen receptor T-cell therapy for colorectal cancer
Terlikowska KM, Terlikowski SJ (2021) Chimeric antigen receptor design and efficacy in ovarian cancer treatment
Tian Y, Li Y, Shao Y, Zhang Y (2020) Gene modification strategies for next- generation CAR T cells against solid cancers. J Hematol Oncol 6:1–16
Google Scholar
Transl J, Land CA, Musich PR, Haydar D, Krenciute G, Xie Q (2020) Chimeric antigen receptor T - cell therapy in glioblastoma : charging the T cells to fight. J Transl Med. https://doi.org/10.1186/s12967-020-02598-0
Article
Google Scholar
Tavernier SJ, Athanasopoulos V, Verloo P, Behrens G, Staal J, Bogaert DJ, Naesens L, De Bruyne M, Van Gassen S, Parthoens E, Ellyard J, Cappello J, Morris LX, Van Gorp H, Van Isterdael G, Saeys Y, Lamkanfi M, Schelstraete P, Dehoorne J, Bordon V, Van Coster R, Lambrecht BN, Menten B, Beyaert R, Vinuesa CG, Heissmeyer V, Dullaers M, Haerynck F (2019) A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation. Nat Commun. https://doi.org/10.1038/s41467-019-12704-6
Article
PubMed
PubMed Central
Google Scholar
Tellez-gabriel M, Ory B, Lamoureux F, Heymann M, Heymann D (2012) Tumour heterogeneity: the key advantages of single-cell analysis. Int J Mol Sci. https://doi.org/10.3390/ijms17122142
Article
Google Scholar
Toulouie S, Johanning G, Shi Y (2021) Chimeric antigen receptor T-cell immunotherapy in breast cancer: development and challenges. J Cancer 12:1212–1219. https://doi.org/10.7150/JCA.54095
Article
CAS
PubMed
PubMed Central
Google Scholar
Waldman AD, Fritz JM, Lenardo MJ (2020) A guide to cancer immunotherapy: from T cell basic science to clinical practice. Nat Rev Immunol. https://doi.org/10.1038/s41577-020-0306-5
Article
PubMed
PubMed Central
Google Scholar
Ware MB, El- BF, Lesinski GB (2020) Mirage or long–awaited oasis: cell responses in pancreatic cancer. J Immunother Cancer 8:e001100. https://doi.org/10.1136/jitc-2020-001100
Article
PubMed
PubMed Central
Google Scholar
Wen H, Qu Z, Yan Y, Pu C, Wang C, Jiang H, Hou T, Huo Y (2019) Preclinical safety evaluation of chimeric antigen receptor-modified T cells against CD19 in NSG mice. Ann Transl Med 7:735–735. https://doi.org/10.21037/atm.2019.12.03
Article
CAS
PubMed
PubMed Central
Google Scholar
Wiebking V, Lee CM, Mostrel N, Lahiri P, Bak R, Bao G, Roncarolo MG, Bertaina A, Porteus MH (2021) Genome editing of donor-derived T cells to generate allogeneic chimeric antigen receptor-modified T cells: optimizing aβ T-cell-depleted haploidentical hematopoietic stem cell transplantation. Haematologica 106:847–858. https://doi.org/10.3324/haematol.2019.233882
Article
CAS
PubMed
Google Scholar
Wang M, Zhao J, Zhang L, Wei F, Lian Y, Wu Y, Gong Z (2017) Role of tumor microenvironment in tumorigenesis. J Cancer 8:761–773. https://doi.org/10.7150/jca.17648
Article
CAS
PubMed
PubMed Central
Google Scholar
Wrona E, Borowiec M, Potemski P (2021) CAR-NK cells in the treatment of solid tumors. Int J Mol Sci 22:5899
Article
CAS
Google Scholar
Wu P, Gao W, Su M, Nice EC, Zhang W, Lin J (2021) Adaptive mechanisms of tumor therapy resistance driven by tumor microenvironment. Front Cell Dev Biol 9:1–23. https://doi.org/10.3389/fcell.2021.641469
Article
CAS
Google Scholar
Xie Q, Ding J, Chen Y (2021) Role of CD8 D T lymphocyte cells: Interplay with stromal cells in tumor microenvironment. Acta Pharm Sin B 11:1365–1378. https://doi.org/10.1016/j.apsb.2021.03.027
Article
CAS
PubMed
PubMed Central
Google Scholar
Xiao BF, Zhang JT, Zhu YG, Cui XR, Lu ZM, Yu BT, Wu N (2021) Chimeric antigen receptor T-cell therapy in lung cancer: potential and challenges. Front Immunol 12:1–16. https://doi.org/10.3389/fimmu.2021.782775
Article
Google Scholar
Yanagihara Y, Ikizawa K, Kajiwara K (1995) Functional significance of IL-4 receptor on B cells in IL-4-induced human IgE production. J Allergy Clin Immunol 96:1145–1151
Article
CAS
Google Scholar
Zaman R, Islam RA, Ibnat N, Othman I, Zaini A, Lee CY, Chowdhury EH (2019) Current strategies in extending half-lives of therapeutic proteins. J Control Release 301:176–189. https://doi.org/10.1016/j.jconrel.2019.02.016
Article
CAS
PubMed
Google Scholar
Zambrano-Zaragoza ML, González-Reza R, Mendoza-Muñoz N, Miranda-Linares V, Bernal-Couoh TF, Mendoza-Elvira S, Quintanar-Guerrero D (2018) Nanosystems in edible coatings: a novel strategy for food preservation. Int J Mol Sci. https://doi.org/10.3390/ijms19030705
Article
PubMed
PubMed Central
Google Scholar
Zhang Q, Ping J, Huang Z, Zhang X, Zhou J, Wang G, Liu S, Ma J (2020) Review article CAR-T cell therapy in cancer: tribulations and road ahead 2020
Zhang Z, Miao L, Ren Z, Tang F, Li Y, Fantini M, Golubovskaya V, Biotechnologies P (2021) Gene-edited interleukin CAR-T cells therapy in the treatment of malignancies : present and future. Front Immunol 12:1–13. https://doi.org/10.3389/fimmu.2021.718686
Article
CAS
Google Scholar
Zhylko A, Winiarska M, Graczyk-Jarzynka A (2020) The great war of today: modifications of CAR-T cells to effectively combat malignancies. Cancers 12:2030
Article
CAS
Google Scholar
Zhang Y, Guan X, Jiang P (2020) Cytokine and chemokine signals of T-cell exclusion in tumors. Front Immunol 11:1–20. https://doi.org/10.3389/fimmu.2020.594609
Article
CAS
Google Scholar
Zhao L, Cao YJ (2019) Engineered T cell therapy for cancer in the clinic. Front Immunol. https://doi.org/10.3389/fimmu.2019.02250
Article
PubMed
PubMed Central
Google Scholar